LGI2 抗体 (Center)
Quick Overview for LGI2 抗体 (Center) (ABIN500156)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
特异性
- This antibody detetcs LGI2 at center. It will recognize only the longest isoform. The antibody is predicted to be specific to LGI2 and not recognize other LGI proteins.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- LGI2 antibody was raised against a 10 amino acid peptide from near the center of human LGI2.
-
亚型
- IgG
-
-
anti-Leucine-Rich Repeat LGI Family, Member 2 (LGI2) (AA 194-310) antibody
LGI2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat LGI Family, Member 2 (LGI2) (AA 446-545) antibodyLGI2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Leucine-Rich Repeat LGI Family, Member 2 (LGI2) (AA 170-219) antibodyLGI2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))
-
别名
- LGI2
-
背景
- The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE. Three isoforms of LGI2 are known to exist.Synonyms: KIAA1916, LGI1-like protein 2, LGI2, LGIL2, Leucine-rich glioma-inactivated protein 2, Leucine-rich repeat LGI family member 2
-
基因ID
- 55203
-
NCBI登录号
- NP_060646
-
UniProt
- Q8N0V4
抗原
-
