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LGI1 抗体 (N-Term)

This anti-LGI1 antibody is a 兔 多克隆 antibody detecting LGI1 in WB 和 EIA. Suitable for 小鼠, 人 和 大鼠.
产品编号 ABIN500152
发货至: 中国

Quick Overview for LGI1 抗体 (N-Term) (ABIN500152)

抗原

See all LGI1 抗体
LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

适用

  • 41
  • 26
  • 15
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
小鼠, 人, 大鼠

宿主

  • 28
  • 23

克隆类型

  • 28
  • 23
多克隆

标记

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  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LGI1 antibody is un-conjugated

应用范围

  • 50
  • 24
  • 14
  • 14
  • 13
  • 13
  • 13
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 17
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody detects LGI1 at N-term. It is predicted to be specific to LGI1 and not recognize other LGI proteins.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    LGI1 antibody was raised against a 13 amino acid peptide from near the amino terminus of human LGI1.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL. Two isoforms of LGI1 are known to exist, but the top band seenin the western blot is likely to be non-specific.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

    别名

    LGI1 / EPT

    背景

    The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.Synonyms: Epitempin-1, Leucine-rich glioma-inactivated protein 1

    基因ID

    9211

    UniProt

    O95970
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