FAIM2 抗体 (N-Term)
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Quick Overview for FAIM2 抗体 (N-Term) (ABIN500148)
抗原
See all FAIM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects FAIM2.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- LFG antibody was raised against a 16 amino acid peptide from near the amino terminus of human LFG.
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亚型
- IgG
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anti-Fas Apoptotic Inhibitory Molecule 2 (FAIM2) (AA 1-316) antibody
FAIM2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 2 (FAIM2) (AA 1-316) antibodyFAIM2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Fas Apoptotic Inhibitory Molecule 2 (FAIM2) (AA 1-105) antibodyFAIM2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))
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别名
- FAIM2
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背景
- Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. LFG is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-? death signal. In this respect, LFG is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. LFG, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. LFG is widely distributed, but highly expressed in the hippocampus and other neural tissues. LFG was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.Synonyms: Fas apoptotic inhibitory molecule 2, KIAA0950, LFG, Protein lifeguard, TMBIM2, Transmembrane BAX inhibitor motif-containing protein 2
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基因ID
- 23017
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UniProt
- Q9BWQ8
抗原
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