LASS5 抗体 (N-Term)
Quick Overview for LASS5 抗体 (N-Term) (ABIN500140)
抗原
See all LASS5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects LASS5 at N-term. It may cross-react with the highly homologous LASS6.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- LASS5 antibody was raised against a 18 amino acid peptide near the amino terminus of the human LASS5.
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亚型
- IgG
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anti-LAG1 Homolog, Ceramide Synthase 5 (LASS5) (AA 332-392) antibody
LASS5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-LAG1 Homolog, Ceramide Synthase 5 (LASS5) (AA 101-200) antibodyLASS5 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-LAG1 Homolog, Ceramide Synthase 5 (LASS5) (AA 71-120) antibodyLASS5 适用: 人, 兔, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-LAG1 Homolog, Ceramide Synthase 5 (LASS5) (AA 72-121) antibodyLASS5 适用: 人, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-LAG1 Homolog, Ceramide Synthase 5 (LASS5) (AA 1-100) antibodyLASS5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-LAG1 Homolog, Ceramide Synthase 5 (LASS5) (C-Term) antibodyLASS5 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))
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别名
- LASS5
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背景
- The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia. Recent studies show that LASS5 partially correct growth and apoptosis. Multiple isoforms of LASS5 are known to exist.Synonyms: LAG1 longevity assurance homolog 5, LASS5, TRAM homolog 4, TRH4, Translocating chain-associating membrane protein homolog 4
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基因ID
- 91012
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NCBI登录号
- NP_671723
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UniProt
- Q8N5B7
抗原
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