LRRC1 抗体 (C-Term)
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Quick Overview for LRRC1 抗体 (C-Term) (ABIN500136)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects LRRC1.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- Lano antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human Lano.
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亚型
- IgG
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anti-Leucine Rich Repeat Containing 1 (LRRC1) (AA 265-524) antibody
LRRC1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 1 (LRRC1) (AA 298-330) antibodyLRRC1 适用: 人 WB 宿主: 兔 Polyclonal RB30744 unconjugated
anti-Leucine Rich Repeat Containing 1 (LRRC1) (C-Term) antibodyLRRC1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 斑马鱼, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 -2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))
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别名
- LRRC1
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背景
- Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble (1). The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells (2). Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions (1,3). It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues (4,5).Synonyms: LANO, LANO adapter protein, LAP and no PDZ protein, LRRC1, Leucine-rich repeat-containing protein 1
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基因ID
- 55227
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UniProt
- Q9BTT6
抗原
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