KLHL1 抗体 (N-Term)
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Quick Overview for KLHL1 抗体 (N-Term) (ABIN500126)
抗原
See all KLHL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Kelch-like 1 protein.
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交叉反应 (详细)
- Species reactivity (tested):Human, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- KLHL1 antibody was raised against a 14 amino acid peptide from near the amino-terminus of human KLHL1.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 2 - 4 μg/mL. Human brain cell lysate can be used as positive control. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- KLHL1 (Kelch-Like 1 (KLHL1))
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背景
- The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues (1,2). The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins (3). Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression (1).Synonyms: KIAA1490, KLHL1
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基因ID
- 57626
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UniProt
- Q9NR64
抗原
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