FERMT3 抗体 (C-Term)
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Quick Overview for FERMT3 抗体 (C-Term) (ABIN500122)
抗原
See all FERMT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects FERMT3.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- KINDLIN3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of the human KINDLIN3.
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亚型
- IgG
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anti-Fermitin Family Member 3 (FERMT3) (C-Term) antibody
FERMT3 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (AA 1-663) antibodyFERMT3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (AA 106-371) antibodyFERMT3 适用: 人, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (AA 388-503) antibodyFERMT3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (AA 117-151) antibodyFERMT3 适用: 小鼠 WB 宿主: 兔 Polyclonal RB56300 unconjugated
anti-Fermitin Family Member 3 (FERMT3) (C-Term) antibodyVerified FERMT3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Fermitin Family Member 3 (FERMT3) (AA 1-663) antibodyFERMT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- FERMT3 (Fermitin Family Member 3 (FERMT3))
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别名
- FERMT3
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背景
- The three KINDLINs are a novel family of focal adhesion proteins, localizing to integrin adhesion sites. The KINDLIN proteins are composed of a centrally located FERM domain interrupted by a pleckstrin homology (PH) domain. KINDLIN1 and KINDLIN2 have been shown to play an essential role in integrin-mediated adhesion and spreading. In contrast to the widely expressed KINDLIN1 and KINDLIN2, KINDLIN3 is restricted to hematopoietic cells and is particularly abundant in megakaryocytes and platelets. Several reports describe a transcriptional misregulation of KINDLINs in various types of cancer. A recent study demonstrates that KINDLIN3 is essential for platelet integrin activation and subsequent integrin outside-in signaling, suggesting it may serve as a potential target for the design of therapeutics aimed at specifically disrupting integrin activation in platelets and leukocytes.Synonyms: Fermitin family homolog 3, KIND3, Kindlin-3, MIG2-like protein, MIG2B, URP2, Unc-112-related protein 2
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基因ID
- 83706
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NCBI登录号
- NP_848537
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UniProt
- Q86UX7
抗原
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