Retinoic Acid Induced 12 (RAI12) 抗体 (AbBy Fluor® 680)
Quick Overview for Retinoic Acid Induced 12 (RAI12) 抗体 (AbBy Fluor® 680) (ABIN5001188)
抗原
See all Retinoic Acid Induced 12 (RAI12) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DERP6/C17orf81
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亚型
- IgG
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anti-Retinoic Acid Induced 12 (RAI12) (C-Term) antibody
RAI12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Induced 12 (RAI12) (AA 143-192) antibodyRAI12 适用: 人, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Induced 12 (RAI12) (AA 17-316) antibodyRAI12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Induced 12 (RAI12) (C-Term) antibodyRAI12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Retinoic Acid Induced 12 (RAI12)
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别名
- DERP6
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背景
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Synonyms: MST071, MSTP071, chromosome 17 open reading frame 81, Dermal papilla derived protein 6, dermal papilla-derived protein 6, DERP6, HSPC002, S phase 2 protein, ELP5_HUMAN.
Background: DERP6, is a 316 amino acid protein that localizes to the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed ubiquitously with highest expression in liver, heart, testis, brain and skeletal muscle, DERP6 is thought to be involved in p53-mediated transcriptional regulation. The gene encoding DERP6 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
抗原
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