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NKIRAS1 抗体 (Center)

This anti-NKIRAS1 antibody is a 兔 多克隆 antibody detecting NKIRAS1 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500110
发货至: 中国

Quick Overview for NKIRAS1 抗体 (Center) (ABIN500110)

抗原

See all NKIRAS1 抗体
NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This NKIRAS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Center

    特异性

    This antibody detects both kappaB-ras1 and kappaB-ras2.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide afinity chromatography

    免疫原

    KappaB ras antibody was raised against a 18 amino acid peptide from near the center of human KappaB ras 1.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

    别名

    NKIRAS1

    背景

    KappaB ras-1 (kappaB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkappaB (IkappaB), an inhibitor of the transcription factor NF-kappaB. IkappaB exists in two homologous forms, IkappaB-alpha and IkappaB-beta, although IkappaB-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive IkappaB-alpha-NF-kappaB complexes can shuttle in and out of the nucleus, IkappaB-beta-NF-kappaB complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the IkappaB-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of IkappaB-beta and regulating the rate of degradation of IkappaB-beta.Synonyms: KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1

    基因ID

    28512

    UniProt

    Q9NYS0
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