Junctophilin 1 抗体 (C-Term)
Quick Overview for Junctophilin 1 抗体 (C-Term) (ABIN500094)
抗原
See all Junctophilin 1 (JPH1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- This antibody detects JPH1.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- JPH1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human JPH1.
-
亚型
- IgG
-
-
anti-Junctophilin 1 (JPH1) (AA 1-201) antibody
JPH1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 1 (JPH1) (AA 431-546) antibodyJPH1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 1 (JPH1) (AA 501-579) antibodyJPH1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Junctophilin 1 (JPH1) (AA 501-579) antibodyJPH1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Junctophilin 1 (JPH1) (C-Term) antibodyJPH1 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 1 (JPH1) (AA 542-591) antibodyJPH1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- Junctophilin 1 (JPH1)
-
背景
- Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain and contribute to the subsurface cistern formation in neurons. JPH1 is essential for stabilizing the T-tubule and SR membranes to form junctions and provide an environment for the assembly of receptors such as the ryanodine receptor type 1 (RyR1).Synonyms: JP1
-
基因ID
- 56704
-
NCBI登录号
- NP_065698
-
UniProt
- Q9HDC5
抗原
-
