JMJD1C 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for JMJD1C 抗体 (N-Term) (ABIN500078)
抗原
See all JMJD1C 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody detects JMJD1C / TRIP8. It will not cross-react with JMJD1A or JMJD1B.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- JMJD1C antibody was raised against a 20 amino acid peptide from near the amino terminus of human JMJD1C.
-
亚型
- IgG
-
-
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2-99) antibody
JMJD1C 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 539-648) antibodyJMJD1C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2-99) antibodyJMJD1C 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3A8 unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2019-2051) antibodyJMJD1C 适用: 人 WB 宿主: 兔 Polyclonal RB55072 unconjugated
-
-
应用备注
-
ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
-
别名
- JMJD1C / TRIP8
-
背景
- The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.Synonyms: JHDM2C, Jumonji domain-containing protein 1C, KIAA1380, Probable JmjC domain-containing histone demethylation protein 2C, Thyroid receptor-interacting protein 8
-
基因ID
- 221037
-
NCBI登录号
- NP_116165
-
UniProt
- Q15652
-
途径
- Nuclear Hormone Receptor Binding
抗原
-
