KDM3B 抗体 (Center)
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北京 101111
Quick Overview for KDM3B 抗体 (Center) (ABIN500076)
抗原
See all KDM3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects JMJD1B. It will not cross-react with JMJD1A or JMJD1C.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- JMJD1B antibody was raised against a 20 amino acid peptide from near the center of human JMJD1B.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1059-1283) antibody
KDM3B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1601-1761) antibodyKDM3B 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (Internal Region) antibodyKDM3B 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1-759) antibodyKDM3B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1691-1740) antibodyKDM3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 小鸡, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (C-Term) antibodyKDM3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 非洲爪蟾, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 869-897) antibodyKDM3B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14344 unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1328-1358), (C-Term) antibodyKDM3B 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal RB14629 unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 876-905), (Middle Region) antibodyKDM3B 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1335-1358), (C-Term) antibodyKDM3B 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
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别名
- JMJD1B / KDM3B
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背景
- The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene. Besides CD34+ cells and acute myeloid leukemia (AML) cell lines, JMJD1B mRNA is highly expressed in liver, heart, kidney, skeletal muscle, and placenta tissues. The JMJD1B gene is localized to a region of chromosome 5q31, which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor. In contrast, JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung cancers indicating that the role of JMJD1B in cancer formation and progression is more complex than originally postulated. At least three isoforms of JMJD1B are known to exist.Synonyms: 5qNCA, C5orf7, JHDM2B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, KIAA1082, Lysine-specific demethylase 3B, Nuclear protein 5qNCA
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基因ID
- 51780
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NCBI登录号
- NP_057688
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UniProt
- Q7LBC6
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途径
- Warburg Effect
抗原
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