IRGC 抗体 (C-Term)
This anti-IRGC antibody is a 兔 多克隆 antibody detecting IRGC in WB, IF 和 EIA. Suitable for 人, 大鼠 和 小鼠.
Quick Overview for IRGC 抗体 (C-Term) (ABIN500066)
抗原
See all IRGC 抗体
IRGC
(Immunity-Related GTPase Family, Cinema (IRGC))
适用
人, 大鼠, 小鼠
宿主
兔
克隆类型
多克隆
标记
This IRGC antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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特异性
- This antibody detects IRGC at C-term. It will recognize both isoforms.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- IRGC antibody was raised against a 12 amino acid peptide near the carboxy terminus of human IRGC.
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亚型
- IgG
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anti-Immunity-Related GTPase Family, Cinema (IRGC) (C-Term) antibody
IRGC 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Immunity-Related GTPase Family, Cinema (IRGC) (AA 73-122) antibodyIRGC 适用: 人, 大鼠, 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
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别名
- IRGC
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背景
- Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines. As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans. Two isoforms of IRGC are known to exist.Synonyms: Cinema 1, IIGP5, IRGC1, Immunity-related GTPase cinema 1, Interferon-inducible GTPase 5
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基因ID
- 56269
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NCBI登录号
- NP_062558
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UniProt
- Q6NXR0
抗原
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