IRF8 抗体
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北京 101111
Quick Overview for IRF8 抗体 (ABIN500062)
抗原
See all IRF8 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- IRF8 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy-terminus of human IRF8.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human IRF8 Peptide
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亚型
- IgG
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anti-Interferon Regulatory Factor 8 (IRF8) (AA 128-426) antibody
IRF8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (N-Term) antibodyIRF8 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 1-327) antibodyIRF8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (C-Term) antibodyVerified IRF8 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 122-218) antibodyIRF8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (C-Term) antibodyIRF8 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 35-84) antibodyIRF8 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Pig, Bat, 小鸡, Hamster, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 384-409) antibodyIRF8 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 241-269) antibodyIRF8 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 8 (IRF8) (AA 128-426) antibodyIRF8 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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别名
- IRF8 / ICSBP1
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背景
- Interferons (IFN)s are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms (1 for review). During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. Unlike IRF3, IRF8 appears to act as a negative regulator of IFN-induced genes in most cases (2,3), but IRF8 mediates activation of NF-kappaB by the toll-like receptor 9 (TLR9) after stimulation by unmethylated CpG DNA in dendritic cells (4,5). Finally, it has been shown that IRF8 decreases bcl-2 expression and thus may play a role in chronic myelogenous leukemia (6).Synonyms: IRF-8, Interferon consensus sequence-binding protein, Interferon regulatory factor 8
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基因ID
- 3394
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NCBI登录号
- NP_002154
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UniProt
- Q02556
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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