COQ10B 抗体 (AA 38-110) (AbBy Fluor® 750)
Quick Overview for COQ10B 抗体 (AA 38-110) (AbBy Fluor® 750) (ABIN5000414)
抗原
See all COQ10B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 38-110
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特异性
- Cross-reactivity with COQ10A (91 % homology with the immunogen sequence),
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human COQ10B
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亚型
- IgG
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anti-Coenzyme Q10 Homolog B (COQ10B) (AA 38-150) antibody
COQ10B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coenzyme Q10 Homolog B (COQ10B) (AA 38-238) antibodyCOQ10B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- COQ10B (Coenzyme Q10 Homolog B (COQ10B))
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别名
- COQ10B
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背景
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Synonyms: Coenzyme Q10, Coenzyme Q10 B, Coenzyme Q10 homolog B, Coenzyme Q10B, CQ10B_HUMAN.
Background: COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.
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基因ID
- 80219
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UniProt
- Q9H8M1
抗原
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