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NLRC4 抗体

This anti-NLRC4 antibody is a 兔 多克隆 antibody detecting NLRC4 in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN500034
发货至: 中国

Quick Overview for NLRC4 抗体 (ABIN500034)

抗原

See all NLRC4 抗体
NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

适用

  • 33
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宿主

  • 21
  • 9
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克隆类型

  • 22
  • 11
多克隆

标记

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  • 1
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This NLRC4 antibody is un-conjugated

应用范围

  • 21
  • 14
  • 10
  • 6
  • 5
  • 2
  • 1
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  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    Ipaf antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of human Ipaf.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human Ipaf / CARD12 / CLANA Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 0.5 to 2 μg/mL. Human peripheral blood leukocyte (PBL) cell lysate can beused as positive control and a 110 kDa band can be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

    别名

    NLRC4

    背景

    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NF-kappaB signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family (1). Ipaf (ICE protease activating factor) is a CED-4/Apaf-1 family member that activates caspase-1/ICE and can induce apoptosis in human cells in a caspase-1 dependent manner (2,3). Ipaf and caspase-1 are thought to interact with each other through the association of the Ipaf amino-terminal CARD (caspase recruitment domain) and amino-terminal CARD of caspase-1.Synonyms: CARD12, CLAN, CLAN1, IPAF, NLR family CARD domain-containing protein 4

    基因ID

    58484

    NCBI登录号

    NP_067032

    UniProt

    Q9NPP4

    途径

    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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