ILP-2 抗体
This anti-ILP-2 antibody is a 兔 多克隆 antibody detecting ILP-2 in WB, IF 和 EIA. Suitable for 人, 大鼠 和 小鼠.
Quick Overview for ILP-2 抗体 (ABIN500020)
抗原
See all ILP-2 (BIRC8) 抗体
ILP-2 (BIRC8)
(Baculoviral IAP Repeat-Containing 8 (BIRC8))
适用
人, 大鼠, 小鼠
宿主
兔
克隆类型
多克隆
标记
This ILP-2 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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特异性
- ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human ILP-2 Peptide
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亚型
- IgG
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anti-Baculoviral IAP Repeat-Containing 8 (BIRC8) (AA 1-236) antibody
BIRC8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 to 2 μg/mL. Human HepG2 or MOLT4 cell lysate can be used as a positivecontrol and a band at approximately 33 kDa can be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
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别名
- BIRC8 / ILP2
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背景
- Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.Synonyms: Baculoviral IAP repeat-containing protein 8, IAP-like protein 2, ILP-2, Inhibitor of apoptosis-like protein 2, Testis-specific inhibitor of apoptosis
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基因ID
- 112401
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NCBI登录号
- NP_203127
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UniProt
- Q96P09
抗原
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