IL32 抗体 (Intermediate Domain)
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Quick Overview for IL32 抗体 (Intermediate Domain) (ABIN500010)
抗原
See all IL32 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Intermediate Domain
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特异性
- IL-32 antibody was raised against a 16 amino acid peptide from near the center of human IL-32.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human IL-32 (Intermediate Domain) Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 2.5 - 5 μg/mL. This antibody detects the largest isoform of IL-32.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- IL32 (Interleukin 32 (IL32))
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别名
- Interleukin-32 / IL32
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背景
- Interleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2 . It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32 (2). IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-alpha, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFNgamma, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis (3).Synonyms: IL-32, NK4, Natural killer cells protein 4, TAIF, Tumor necrosis factor alpha-inducing factor
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基因ID
- 9235
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UniProt
- P24001
抗原
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