IL27 抗体 (N-Term)
Quick Overview for IL27 抗体 (N-Term) (ABIN500000)
抗原
See all IL27 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to IL-27.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Affinity chromatography purified via peptide column
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亚型
- IgG
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anti-Interleukin-27 Subunit alpha (IL27) antibody
IL27 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 Subunit alpha (IL27) (AA 1-173) antibodyIL27 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 Subunit alpha (IL27) (AA 29-234) antibodyIL27 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 Subunit alpha (IL27) (AA 32-234) antibodyIL27 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 Subunit alpha (IL27) antibody (FITC)IL27 适用: 人 FACS 宿主: 小鼠 Monoclonal B-G49 FITC
anti-Interleukin-27 Subunit alpha (IL27) (AA 29-234) antibodyIL27 适用: 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 2 - 4 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- IL27 (Interleukin-27 Subunit alpha (IL27))
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别名
- Interleukin-27 / IL27A
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背景
- Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-γ, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
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基因ID
- 246778
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NCBI登录号
- NP_663634
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UniProt
- Q8NEV9
抗原
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