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IL27 抗体 (N-Term)

This anti-IL27 antibody is a 兔 多克隆 antibody detecting IL27 in WB, EIA 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN500000
发货至: 中国
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Quick Overview for IL27 抗体 (N-Term) (ABIN500000)

抗原

See all IL27 抗体
IL27 (Interleukin-27 Subunit alpha (IL27))

适用

  • 16
  • 13
  • 12
人, 小鼠

宿主

  • 17
  • 4

克隆类型

  • 17
  • 4
多克隆

标记

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL27 antibody is un-conjugated

应用范围

  • 9
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody reacts to IL-27.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Affinity chromatography purified via peptide column

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 2 - 4 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    IL27 (Interleukin-27 Subunit alpha (IL27))

    别名

    Interleukin-27 / IL27A

    背景

    Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-γ, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28

    基因ID

    246778

    NCBI登录号

    NP_663634

    UniProt

    Q8NEV9
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