FBXO43 抗体 (C-Term)
Quick Overview for FBXO43 抗体 (C-Term) (ABIN499982)
抗原
See all FBXO43 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- IL-1RAcP antibody was raised against a peptide corresponding to amino acids 525 to 540 of human IL-1RAcP, which is identical to those of mouse and rat origins. This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human IL-1RAcP (C-Terminus 2) Peptide
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亚型
- IgG
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anti-F-Box Protein 43 (FBXO43) (AA 1-110) antibody
FBXO43 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B6 unconjugated
anti-F-Box Protein 43 (FBXO43) (C-Term) antibodyVerified FBXO43 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-F-Box Protein 43 (FBXO43) (C-Term) antibodyFBXO43 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 43 (FBXO43) (AA 668-694), (C-Term) antibodyFBXO43 适用: 人 WB 宿主: 兔 Polyclonal RB42859 unconjugated
anti-F-Box Protein 43 (FBXO43) (N-Term) antibodyFBXO43 适用: 人, 小鼠, 大鼠, Chimpanzee WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1/1000 to 1/2000 dilution. An approximately 66 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- FBXO43 (F-Box Protein 43 (FBXO43))
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别名
- FBXO43
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背景
- The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NFkappa-B inducing kinae (NIK) and of NF-kappaB, recruits to the IL-1R complex through IL-1RAcP (2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP (3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.Synonyms: EMI2, Endogenous meiotic inhibitor 2, F-box only protein 43, FBP5B
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基因ID
- 100101275
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UniProt
- Q8AXF4
抗原
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