FBXO43 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for FBXO43 抗体 (C-Term) (ABIN499982)
抗原
See all FBXO43 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- IL-1RAcP antibody was raised against a peptide corresponding to amino acids 525 to 540 of human IL-1RAcP, which is identical to those of mouse and rat origins. This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- Human IL-1RAcP (C-Terminus 2) Peptide
-
亚型
- IgG
-
-
anti-F-Box Protein 43 (FBXO43) (C-Term) antibody
Verified FBXO43 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-F-Box Protein 43 (FBXO43) (AA 1-110) antibodyFBXO43 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B6 unconjugated
anti-F-Box Protein 43 (FBXO43) (C-Term) antibodyFBXO43 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 43 (FBXO43) (AA 668-694), (C-Term) antibodyFBXO43 适用: 人 WB 宿主: 兔 Polyclonal RB42859 unconjugated
anti-F-Box Protein 43 (FBXO43) (N-Term) antibodyFBXO43 适用: 人, 小鼠, 大鼠, Chimpanzee WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western Blot: 1/1000 to 1/2000 dilution. An approximately 66 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
-
- FBXO43 (F-Box Protein 43 (FBXO43))
-
别名
- FBXO43
-
背景
- The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NFkappa-B inducing kinae (NIK) and of NF-kappaB, recruits to the IL-1R complex through IL-1RAcP (2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP (3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.Synonyms: EMI2, Endogenous meiotic inhibitor 2, F-box only protein 43, FBP5B
-
基因ID
- 100101275
-
UniProt
- Q8AXF4
抗原
-
