IER3 抗体 (Center)
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北京 101111
Quick Overview for IER3 抗体 (Center) (ABIN499960)
抗原
See all IER3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody reacts to IEX1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- IEX1 antibody was raised against a 24 amino acid peptide near the center of human IEX1.
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亚型
- IgG
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anti-Immediate Early Response 3 (IER3) (AA 45-73), (N-Term) antibody
IER3 适用: 人, 小鼠 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (C-Term) antibodyIER3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (AA 38-65), (N-Term) antibodyIER3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB20475 unconjugated
anti-Immediate Early Response 3 (IER3) (AA 85-156) antibodyIER3 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (AA 1-82) antibodyIER3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 2 - 4 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- IER3 (Immediate Early Response 3 (IER3))
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别名
- IER3 / IEX1
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背景
- IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-a. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kappaB/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.Synonyms: DIF2, Differentiation-dependent gene 2 protein, GLY96, IEX-1, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, PRG1, Radiation-inducible immediate-early gene IEX-1
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基因ID
- 8870
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UniProt
- P46695
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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