INSM1 抗体 (N-Term)
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Quick Overview for INSM1 抗体 (N-Term) (ABIN499952)
抗原
See all INSM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to IA-1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- IA-1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human IA-1.
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亚型
- IgG
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anti-Insulinoma-Associated 1 (INSM1) (AA 81-125), (N-Term) antibody
INSM1 适用: 人 IHC 宿主: 兔 Monoclonal 456R unconjugated Recombinant Antibody
anti-Insulinoma-Associated 1 (INSM1) (AA 278-518) antibodyINSM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulinoma-Associated 1 (INSM1) antibodyINSM1 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Insulinoma-Associated 1 (INSM1) (AA 191-240) antibodyINSM1 适用: 人, 小鼠, 犬, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulinoma-Associated 1 (INSM1) (C-Term) antibodyINSM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulinoma-Associated 1 (INSM1) (Middle Region) antibodyINSM1 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- INSM1 (Insulinoma-Associated 1 (INSM1))
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别名
- INSM1 / IA1
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背景
- IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100 % of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.Synonyms: Insulinoma-associated protein 1, Zinc finger protein IA-1
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基因ID
- 3642
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NCBI登录号
- NP_002187
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UniProt
- Q01101
抗原
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