HAAO 抗体 (N-Term)
Quick Overview for HAAO 抗体 (N-Term) (ABIN499940)
抗原
See all HAAO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- HAAO antibody was raised against a 17 amino acid peptide near the amino terminus of human HAAO.
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亚型
- IgG
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anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 153-223) antibody
HAAO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 97-196) antibodyHAAO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) antibodyHAAO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 101-200) antibodyHAAO 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 72-121) antibodyHAAO 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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别名
- HAAO
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背景
- HAAO (3-Hydroxyanthranilate 3,4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. Furthermore, recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer.Synonyms: 3-HAO, 3-hydroxyanthranilate 3, 3-hydroxyanthranilate oxygenase, 3-hydroxyanthranilic acid dioxygenase, 4-dioxygenase, HAD
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基因ID
- 23498
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NCBI登录号
- NP_036337
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UniProt
- P46952
抗原
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