GRIK4 抗体 (N-Term)
Quick Overview for GRIK4 抗体 (N-Term) (ABIN499930)
抗原
See all GRIK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Grik4 antibody was raised against a 14 amino acid peptide near the amino terminus of the human Grik4.
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 21-166) antibody
GRIK4 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8H5G5 unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 826-956) antibodyGRIK4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 21-130) antibodyGRIK4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 225-447) antibodyGRIK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 21-220) antibodyGRIK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (C-Term) antibodyGRIK4 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4) (AA 49-61), (Extracellular) antibodyGRIK4 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- GRIK4 (Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4))
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别名
- Glutamate Receptor KA1 / GRIK4
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背景
- Grik4 codes for the KA1 subunit of kainate-type ionotropic glutamate receptors which are critical regulators of network activity that act by modifying neuronal excitability, directly and indirectly, through GABAergic interneurons. Five subunits can assemble to form kainate receptors (KARs): GluR5 (coded by Grik1), GluR6 (coded by Grik2), and GluR7 (coded by Grik3) are the low-affinity subunits, and KA1 and KA2 are the high-affinity subunits. In the adult brain, KARs are located pre- and postsynaptically on pyramidal cells and on interneurons. Kainate receptors on GABA-containing interneurons enhance GABA release and thereby downregulate glutamatergic signaling. KARs have been implicated in numerous psychiatric disorders. Case control studies show significant association of Grik4 with both schizophrenia and bipolar disorder. Despite its predicted molecular weight, Grik4 often migrates at a lower molecular weight in SDS-PAGE.Synonyms: EAA1, Excitatory amino acid receptor 1, Glutamate receptor ionotropic kainate 4
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基因ID
- 2900
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UniProt
- Q16099
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途径
- Synaptic Membrane
抗原
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