GRIK3 抗体 (N-Term)
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Quick Overview for GRIK3 抗体 (N-Term) (ABIN499926)
抗原
See all GRIK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Grik3 antibody was raised against a 13 amino acid peptide near the amino terminus of the Human Grik3.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))
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别名
- GRIK3 / GLUR7
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背景
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik3, also known as glutamate receptor 7, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik3 is highly homologous to the related ionotrophic glutamate receptors Grik2 and Grik1. Grik3 has recently been shown to be an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses as grik3-null mice show significantly reduced short- and long-term synaptic potentiation. Other reports have suggested that different polymorphisms in the Grik3 protein may be associated with neurological defects such as recurrent major depressive disorder and schizophrenia.Synonyms: EAA5, Excitatory amino acid receptor 5, GluR-7, Glutamate receptor 7, Glutamate receptor ionotropic kainate 3
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基因ID
- 2899
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UniProt
- Q13003
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途径
- Synaptic Membrane
抗原
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