GPR3 抗体 (C-Term)
Quick Overview for GPR3 抗体 (C-Term) (ABIN499914)
抗原
See all GPR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to GPR3.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- GPR3 antibody was raised against a 13 amino acid peptide from near the carboxy terminus of human GPR3.
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亚型
- IgG
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anti-G Protein-Coupled Receptor 3 (GPR3) (AA 1-330) antibody
GPR3 适用: 人 ELISA, WB, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3B4-G3 unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (AA 300-330) antibodyGPR3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (Extracellular Domain) antibodyGPR3 适用: 人, 小鼠, 大鼠, 猴, Hamster IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (Extracellular Domain) antibodyGPR3 适用: 人, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (Extracellular Domain) antibodyGPR3 适用: 人, 猴, Cow, 兔 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (Internal Region) antibodyVerified GPR3 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 3 (GPR3) (AA 1-330) antibodyGPR3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- GPR3 (G Protein-Coupled Receptor 3 (GPR3))
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别名
- GPR3 / ACCA
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背景
- GPR3, also known as ACCA, is a G-protein coupled receptor that constitutively activates adenylate cyclase and is highly expressed in the central nervous system. Overexpression of GPR3 stimulates the production of amyloid-b peptide (Ab), the deposition of which is one of the pathological hallmarks of Alzheimer 's disease (AD), while the ablation of GPR3 prevented the accumulation of Ab in vitro and in an AD mouse model. This is of particular interest because of the proximity of a reported candidate Alzheimer 's disease (AD) locus, suggesting that GPR3 may be a potential therapeutic target for the treatment of AD. GPR3 has also been shown to block the proliferation of cerebellar granule cell precursors (GCP) during postnatal development by inhibiting the Shh-induced proliferation of GCP, indicating that GPR3 activation may represent one of the signals that triggers the postnatal cell cycle exit and terminal differentiation of GPCs.Synonyms: ACCA orphan receptor, G-protein coupled receptor 3
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基因ID
- 2827
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UniProt
- P46089
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途径
- cAMP Metabolic Process
抗原
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