GOLPH3 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for GOLPH3 抗体 (N-Term) (ABIN499904)
抗原
See all GOLPH3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- GOLPH3 antibody was raised against a 14 amino acid peptide from near the amino terminus of human GOLPH3.
-
亚型
- IgG
-
-
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (AA 16-150) antibody
GOLPH3 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (C-Term) antibodyGOLPH3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) antibodyKD Validated GOLPH3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB7340 unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (AA 251-279), (C-Term) antibodyGOLPH3 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18063 unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (AA 1-30), (N-Term) antibodyGOLPH3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18062 unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (AA 1-298) antibodyGOLPH3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (Internal Region) antibodyVerified GOLPH3 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) antibodyGOLPH3 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) antibodyGOLPH3 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) antibodyGOLPH3 适用: 人 WB 宿主: 小鼠 Monoclonal 9A1 unconjugated
-
-
应用备注
-
ELISA. Western Blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the antibody (in aliquots) at -20 °C.
-
-
- GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))
-
别名
- Golgi Phosphoprotein 3 / GOLPH3
-
背景
- GOLPH3 was initially identified as a peripheral membrane protein localized to the trans-Golgi network, but others reported it to be primarily a mitochondrial protein that regulated the mitochondrial mass through the regulation of the mitochondria-specific phospholipid cardiolipin. GOLPH3 has since been implicated in the target of rapamycin (TOR) signalling pathway. Its overexpression in transfected cells led to and increase in anchorage-independent growth and cell proliferation in vitro. Furthermore, GOLPH3-transfected cells enhanced S6 Kinase activity in response to growth factor stimulation by EGF. Simultaneously, AKT phosphorylation increased in these cells, while these events were abrogated in GOLPH3 siRNA treated cells compared to control cells, indicating the GOLPH3 can enhance signalling through TOR-associated complexes. These results suggest that GOLPH3 is a bona fide oncogene and may be a useful target for therapeutic strategies.Synonyms: Coat protein GPP34, GPP34, MIDAS, Mitochondrial DNA absence factor
-
基因ID
- 64083
-
UniProt
- Q9H4A6
抗原
-
