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ACBD3 抗体 (N-Term)

This anti-ACBD3 antibody is a 兔 多克隆 antibody detecting ACBD3 in WB 和 EIA. Suitable for 人.
产品编号 ABIN499900
发货至: 中国

Quick Overview for ACBD3 抗体 (N-Term) (ABIN499900)

抗原

See all ACBD3 (Acbd3) 抗体
ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

适用

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宿主

  • 33
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克隆类型

  • 35
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多克隆

标记

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This ACBD3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    GOLPH1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human GOLPH1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

    别名

    ACBD3

    背景

    GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.Synonyms: Acyl-CoA-binding domain-containing protein 3, GOCAP1, GOLPH1, Golgi complex-associated protein 1, Golgi phosphoprotein 1, Golgi resident protein GCP60, PAP7, PBR- and PKA-associated protein 7, Peripheral benzodiazepine receptor-associated protein

    基因ID

    64746

    NCBI登录号

    NP_073572

    UniProt

    Q9H3P7
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