TNFSF18 抗体
Our Local Distributor
北京 101111
Quick Overview for TNFSF18 抗体 (ABIN499890)
抗原
See all TNFSF18 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- GITRL antibody was raised against purified recombinant human GITR ligand.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- Recombinant human GITR ligand
-
亚型
- IgG
-
-
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 101-199) antibody
TNFSF18 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 1-177) antibodyTNFSF18 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 70-199) antibodyTNFSF18 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) antibodyTNFSF18 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 68-177) antibodyTNFSF18 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F7 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibodyTNFSF18 适用: 人 WB, IHC (p), ELISA (Capture) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibodyTNFSF18 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) antibodyTNFSF18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 68-177) antibodyTNFSF18 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 108-157) antibodyTNFSF18 适用: 人, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western Blot: 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C.
-
-
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
-
别名
- TNFSF18 / AITRL
-
背景
- The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kappaB and various mitogen-activated protein kinases (reviewed in 1). The glucocorticoid-induced tumor necrosis factor receptor (GITR) is an emerging member of this family that is expressed on CD4+ CD25+ regulatory T cells and appears to have crucial immune regulation functions (2,3). Its ligand GITRL is expressed in endothelial and antigen-presenting cells (4) and can activate NF-kappaB, induce both pro- and anti-apoptotic effects, inhibit the suppressive activity of regulatory T cells, and co-stimulate responder T cells through GITR (5). Dominant negative forms of NIK and TRAF2 expressed in transfected 293 cells substantially inhibited NF-kappaB activation, suggesting that the GITRL-GITR pathway involves both NIK and TRAF2 (4).Synonyms: AITRL, Activation-inducible TNF-related ligand, GITRL, Glucocorticoid-induced TNF-related ligand, TL6, Tumor necrosis factor ligand superfamily member 18, hGITRL
-
基因ID
- 8995
-
UniProt
- Q9UNG2
抗原
-
