CACYBP 抗体 (AA 61-95) (AbBy Fluor® 680)
Quick Overview for CACYBP 抗体 (AA 61-95) (AbBy Fluor® 680) (ABIN4998899)
抗原
See all CACYBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-95
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CACYBP/S100A6BP
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CACYBP (Calcyclin Binding Protein (CACYBP))
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别名
- CACYBP/S100A6BP
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背景
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Synonyms: SIAH Interacting Protein, CACYBP, Calcyclin binding protein, GIG 5, GIG5, Growth inhibiting gene 5, Calcyclin-binding protein, Siah-interacting protein, Growth inhibiting gene 5 protein, hCacyBP, MGC87971, PNAS 107, PNAS107, RP1 102G20.6, S100A6 binding protein, S100A6BP, SIP.
Background: CacyBP is a 228 amino acid protein encoded by the human gene CACYBP. CacyBP is primarily a nuclear protein that contains one CS domain and one SGS domain. CacyBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CacyBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.
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途径
- Response to Growth Hormone Stimulus
抗原
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