GFRA3 抗体 (Intermediate Domain)
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Quick Overview for GFRA3 抗体 (Intermediate Domain) (ABIN499887)
抗原
See all GFRA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Intermediate Domain
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特异性
- GFR alpha 3 antibody was raised against a peptide corresponding to amino acids from 347 to 360 of murine GFR alpha 3.
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纯化方法
- DEAE
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免疫原
- Human GFR alpha 3 (Intermediate Domain) Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 1/500 to 1/1000. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))
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别名
- GFRA3 / GDNFR-alpha 3
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背景
- Members of the glial cell line-derived neurotrophic factor (GDNF) family including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRalpha and Ret receptor tyrosine kinase GFRbeta (2). Following the findings of GFR?-1 and -2, a novel receptor in GFRalpha family was identified very recently from human and mouse and designated GFRalpha-3. GFRalpha-3 binds persephin, thus, persephin, GFRalpha-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.Synonyms: GDNF family receptor alpha-3, GDNF receptor alpha-3, GFR-alpha-3
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基因ID
- 14587
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UniProt
- O35118
抗原
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