GDF6 抗体 (C-Term)
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Quick Overview for GDF6 抗体 (C-Term) (ABIN499881)
抗原
See all GDF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to GDF6.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- GDF6 antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human GDF6.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- GDF6 (Growth Differentiation Factor 6 (GDF6))
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别名
- BMP13 / GDF6
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背景
- Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.Synonyms: Bone Morphogenetic Protein 13, CDMP2, Cartilage Derived Morphogenetic Protein 2, GDF-16, GDF-6, GDF16
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基因ID
- 392255
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NCBI登录号
- NP_001001557
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UniProt
- Q6KF10
抗原
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