GATA3 抗体 (C-Term)
Quick Overview for GATA3 抗体 (C-Term) (ABIN499877)
抗原
See all GATA3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- GATA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human GATA3.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the antibody (in aliquots) at -20 °C.
-
-
- GATA3 (GATA Binding Protein 3 (GATA3))
-
别名
- GATA3
-
背景
- GATA3 is a zinc finger transcription factor that was first recognized as a possible determinant of T cell development. Later studies demonstrated that it is expressed in trophoblast giant cells and regulates trophoblast-specific genes during development. Specifically, GATA3 is selectively expressed in the trophectoderm of the peri-implantation embryo and regulates CDX2, which is required for the transcriptional repression of the POU5F1/Oct4 and NANOG genes and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Decreased or null-expression expression of GATA3 has also been suggested to play a major role in the development and progression of luminal breast cancer.Synonyms: GATA-3, GATA-binding factor 3, Trans-acting T-cell-specific transcription factor GATA-3
-
基因ID
- 2625
-
NCBI登录号
- NP_001002295
-
UniProt
- P23771
-
途径
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
抗原
-