FTO 抗体 (N-Term)
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北京 101111
Quick Overview for FTO 抗体 (N-Term) (ABIN499863)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to FTO.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- FTO antibody was raised against a 15 amino acid peptide from near the amino terminus of human FTO.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- FTO (Fat Mass and Obesity-Associated (FTO))
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别名
- FTO
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背景
- Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.Synonyms: Fat mass and obesity-associated protein, KIAA1752
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基因ID
- 79068
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UniProt
- Q9C0B1
抗原
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