FNIP2 抗体 (C-Term)
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Quick Overview for FNIP2 抗体 (C-Term) (ABIN499853)
抗原
See all FNIP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to FNIP2.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- FNIP2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human FNIP2.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
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别名
- FNIP2
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背景
- FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49 % identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship. Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.Synonyms: FNIP1-like protein, FNIPL, Folliculin-interacting protein 2, KIAA1450, MAPO1, O6-methylguanine-induced apoptosis 1 protein
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基因ID
- 57600
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NCBI登录号
- NP_065891
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UniProt
- Q9P278
抗原
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