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FBLN3 抗体 (C-Term)

This anti-FBLN3 antibody is a 兔 多克隆 antibody detecting FBLN3 in WB, IF 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN499838
发货至: 中国
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Quick Overview for FBLN3 抗体 (C-Term) (ABIN499838)

抗原

See all FBLN3 抗体
FBLN3 (Fibulin 3 (FBLN3))

适用

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人, 大鼠, 小鼠

宿主

  • 54
  • 10

克隆类型

  • 45
  • 19
多克隆

标记

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This FBLN3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to Fibulin 3.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Fibulin 3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human Fibulin 3.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 0.5 - 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    FBLN3 (Fibulin 3 (FBLN3))

    别名

    Fibulin-3

    背景

    Fibulin 3, also known as epidermal growth factor (EGF)-containing fibulin-like extracellular matrix protein 1 (EFEMP1), is a member of the fibulin family of extracellular glycoproteins, a group of proteins that are widely distributed and frequently associated with vascular and elastic tissues. The fibulin proteins typically contain a tandem array of EGF-like repeats and a fibulin-type COOH-terminal module. Aberrant accumulation of Fibulin 3 in the endoplasmic reticulum of retinal pigment epithelial cells has been shown to be associated with inherited forms of macular degeneration, but the loss of Fibulin 3 expression does not lead to macular degeneration but rather the appearance of hernias due to a reduction of elastic fibers of fascial connective tissue. Recent experiments have shown that expression of Fibulin 3 promotes tumor growth and may thus be a therapeutic target. At least three isoforms of Fibulin 3 are known to exist. This antibody is predicted to not cross-react with other Fibulin proteins.Synonyms: DHRD, DRAD, EFEMP1, EGF-containing fibulin-like extracellular matrix protein 1, Extracellular protein S1-5, FBLN3, FBNL, Fibrillin-like protein, Fibulin 3, MLVT, MTLV, S1-5

    基因ID

    2202

    NCBI登录号

    NP_004096

    UniProt

    Q12805

    途径

    EGFR Signaling Pathway
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