FAM59A 抗体 (C-Term)
This anti-FAM59A antibody is a 兔 多克隆 antibody detecting FAM59A in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for FAM59A 抗体 (C-Term) (ABIN499824)
抗原
See all FAM59A 抗体
FAM59A
(Family with Sequence Similarity 59, Member A (FAM59A))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This FAM59A antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- FAM59A antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human FAM59A.
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亚型
- IgG
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anti-Family with Sequence Similarity 59, Member A (FAM59A) (AA 12-320) antibody
FAM59A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))
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别名
- FAM59A
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背景
- FAM59A, also known as GAREM, was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli. FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated, and this phosphorylation is needed for the binding of Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells, and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar, suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.Synonyms: C18orf11
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基因ID
- 64762
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UniProt
- Q9H706
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途径
- EGFR Signaling Pathway
抗原
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