FAM120A 抗体 (Center)
Quick Overview for FAM120A 抗体 (Center) (ABIN499822)
抗原
See all FAM120A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
特异性
- This antibody reacts to FAM120A.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- FAM120A antibody was raised against an 18 amino acid peptide from near the center of human FAM120A.
-
亚型
- IgG
-
-
anti-Family with Sequence Similarity 120A (FAM120A) antibody
FAM120A 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1501CT803-19-85-5 unconjugated
anti-Family with Sequence Similarity 120A (FAM120A) (AA 468-517) antibodyFAM120A 适用: 人, 大鼠, Cow, 犬, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 120A (FAM120A) (AA 1068-1118) antibodyFAM120A 适用: 人, 小鼠, 大鼠, 兔, 豚鼠 WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 120A (FAM120A) (AA 1-140) antibodyFAM120A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 120A (FAM120A) (Middle Region) antibodyFAM120A 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C.
-
-
- FAM120A (Family with Sequence Similarity 120A (FAM120A))
-
别名
- FAM120A
-
背景
- FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells.Synonyms: C9orf10, Constitutive coactivator of PPAR-gamma-like protein 1, KIAA0183, OSSA, Oxidative stress-associated Src activator, Protein FAM120A
-
基因ID
- 23196
-
NCBI登录号
- NP_055427
-
UniProt
- Q9NZB2
抗原
-
