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FAIM 抗体 (C-Term)

This anti-FAIM antibody is a 兔 多克隆 antibody detecting FAIM in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499820
发货至: 中国

Quick Overview for FAIM 抗体 (C-Term) (ABIN499820)

抗原

See all FAIM 抗体
FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

适用

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  • 1
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人, 小鼠

宿主

  • 55
  • 1

克隆类型

  • 56
多克隆

标记

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  • 1
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This FAIM antibody is un-conjugated

应用范围

  • 24
  • 20
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  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 7
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    • 1
    • 1
    • 1
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    C-Term

    特异性

    This antibody reacts to FAIM.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    FAIM antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human FAIM.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 5 - 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

    别名

    FAIM

    背景

    The susceptibility of primary splenic B cells to Fas-mediated apoptosis is regulated in a receptor-specific fashion. Terminal effectors of B cell Fas-resistance include the known anti-apoptotic proteins Bcl-xL, FLIP, and a recently identified protein termed FAIM. This molecule is broadly expressed in various tissues and exists in at least three isoforms. It is thought that resistance to Fas killing via increased expression of FAIM protects foreign antigen-specific B cells during interactions with FasL-bearing T cells whereas autoreactive B cells are deleted via Fas-dependent cytotoxicity. More recent results have indicated that FAIM interacts with both Trk and p75 neurotrophin receptor and may play a role in promoting neurite outgrowth in different neuronal systems by a mechanism involving the activation of NF-kappaB and the Ras-ERK pathway.Synonyms: FAIM-1, FAIM1, Fas Apoptotic Inhibitory Molecule 1

    基因ID

    55179

    NCBI登录号

    NP_060617

    UniProt

    Q9NVQ4
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