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FEM1B 抗体 (C-Term)

FEM1B 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499814
发货至: 中国
  • 抗原 See all FEM1B 抗体
    FEM1B (Fem-1 Homolog B (FEM1B))
    抗原表位
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    C-Term
    适用
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    人, 大鼠, 小鼠
    宿主
    • 34
    • 1
    克隆类型
    • 34
    • 1
    多克隆
    标记
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    This FEM1B antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    F1A alpha antibody was raised against a peptide corresponding to amino acids 609 to 622 of human F1A alpha. This sequence is identical to the corresponding sequence of mouse FEM1b .
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human F1A alpha Peptide
    亚型
    IgG
    Top Product
    Discover our top product FEM1B Primary Antibody
  • 应用备注
    ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 70 kDa band can be detected. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    FEM1B (Fem-1 Homolog B (FEM1B))
    别名
    FEM1B (FEM1B 产品)
    别名
    F1A-ALPHA antibody, F1AA antibody, FEM1-beta antibody, FEM1B antibody, mKIAA0396 antibody, fem-1 homolog B antibody, protein fem-1 homolog B antibody, fem-1 homolog B L homeolog antibody, fem-1 homolog b (C. elegans) antibody, feminization 1 homolog b (C. elegans) antibody, FEM1B antibody, Fem1b antibody, LOC413692 antibody, fem1b.L antibody, fem1b antibody
    背景
    Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1b (1,2). F1Aalpha/FEM1beta is the homologue of C. elegans sex determining protein FEM-1 (1,2). FEM-1/F1Aalpha is cleaved by CED-3 and caspase (3). FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1 (3). Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues (1,2)Synonyms: F1A-alpha, F1AA, FEM1-beta, Fem-1-like death receptor-binding protein alpha, KIAA0396, Protein fem-1 homolog B
    基因ID
    10116
    UniProt
    Q9UK73
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