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FEM1B 抗体 (C-Term)

This anti-FEM1B antibody is a 兔 多克隆 antibody detecting FEM1B in WB, IHC (p) 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN499814
发货至: 中国
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Quick Overview for FEM1B 抗体 (C-Term) (ABIN499814)

抗原

See all FEM1B 抗体
FEM1B (Fem-1 Homolog B (FEM1B))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

  • 36
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多克隆

标记

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This FEM1B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    F1A alpha antibody was raised against a peptide corresponding to amino acids 609 to 622 of human F1A alpha. This sequence is identical to the corresponding sequence of mouse FEM1b .

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human F1A alpha Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 70 kDa band can be detected. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    FEM1B (Fem-1 Homolog B (FEM1B))

    别名

    FEM1B

    背景

    Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1b (1,2). F1Aalpha/FEM1beta is the homologue of C. elegans sex determining protein FEM-1 (1,2). FEM-1/F1Aalpha is cleaved by CED-3 and caspase (3). FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1 (3). Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues (1,2)Synonyms: F1A-alpha, F1AA, FEM1-beta, Fem-1-like death receptor-binding protein alpha, KIAA0396, Protein fem-1 homolog B

    基因ID

    10116

    UniProt

    Q9UK73
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