FEM1B 抗体 (C-Term)
Quick Overview for FEM1B 抗体 (C-Term) (ABIN499814)
抗原
See all FEM1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- F1A alpha antibody was raised against a peptide corresponding to amino acids 609 to 622 of human F1A alpha. This sequence is identical to the corresponding sequence of mouse FEM1b .
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human F1A alpha Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 70 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- FEM1B (Fem-1 Homolog B (FEM1B))
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别名
- FEM1B
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背景
- Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1b (1,2). F1Aalpha/FEM1beta is the homologue of C. elegans sex determining protein FEM-1 (1,2). FEM-1/F1Aalpha is cleaved by CED-3 and caspase (3). FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1 (3). Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues (1,2)Synonyms: F1A-alpha, F1AA, FEM1-beta, Fem-1-like death receptor-binding protein alpha, KIAA0396, Protein fem-1 homolog B
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基因ID
- 10116
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UniProt
- Q9UK73
抗原
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