TMC6 抗体 (Center)
This anti-TMC6 antibody is a 兔 多克隆 antibody detecting TMC6 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499808
发货至:
中国
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Quick Overview for TMC6 抗体 (Center) (ABIN499808)
抗原
See all TMC6 抗体
TMC6
(Transmembrane Channel-Like 6 (TMC6))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This TMC6 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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抗原表位
- Center
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特异性
- This antibody reacts to EVER1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- EVER1 antibody was raised against a 15 amino acid peptide from near the center of human EVER1.
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亚型
- IgG
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anti-Transmembrane Channel-Like 6 (TMC6) (N-Term) antibody
TMC6 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- TMC6 (Transmembrane Channel-Like 6 (TMC6))
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别名
- TMC6 / EVER1
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背景
- Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes, EVER1 and EVER2, located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family. EVER1 possesses eight trans-membrane domains and two leucine zipper motifs. EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1), suggesting that EVER1 and EVER2 act to regulate cellular zinc balance. At least four isoforms of EVER1 are known to exist. This EVER1 antibody does not cross-react with EVER2.Synonyms: EVIN1, Epidermodysplasia verruciformis protein 1, LAK-4, Transmembrane channel-like protein 6
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基因ID
- 11322
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UniProt
- Q7Z403
抗原
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