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ESX Homeobox 1 抗体 (Center)

ESX1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499804
发货至: 中国
  • 抗原 See all ESX Homeobox 1 (ESX1) 抗体
    ESX Homeobox 1 (ESX1)
    抗原表位
    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    Center
    适用
    • 18
    • 3
    宿主
    • 19
    • 1
    克隆类型
    • 20
    多克隆
    标记
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    This ESX Homeobox 1 antibody is un-conjugated
    应用范围
    • 20
    • 15
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    ESX1 antibody was raised against a 19 amino acid peptide near the center of human ESX1.
    亚型
    IgG
    Top Product
    Discover our top product ESX1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    ESX Homeobox 1 (ESX1)
    别名
    ESX1 (ESX1 产品)
    别名
    ESX1L antibody, ESXR1 antibody, Spx1 antibody, ESX homeobox 1 antibody, extraembryonic, spermatogenesis, homeobox 1 antibody, ESX1 antibody, Esx1 antibody
    背景
    Homeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.Synonyms: ESX1L, ESX1R, Homeobox protein ESX1
    基因ID
    80712
    UniProt
    Q8N693
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