ESX Homeobox 1 抗体 (Center)
Quick Overview for ESX Homeobox 1 抗体 (Center) (ABIN499804)
抗原
See all ESX Homeobox 1 (ESX1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- ESX1 antibody was raised against a 19 amino acid peptide near the center of human ESX1.
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亚型
- IgG
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anti-ESX Homeobox 1 (ESX1) (AA 124-213) antibody
ESX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-ESX Homeobox 1 (ESX1) (N-Term) antibodyESX1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ESX Homeobox 1 (ESX1) (AA 35-84) antibodyESX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ESX Homeobox 1 (ESX1) (N-Term) antibodyESX1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ESX Homeobox 1 (ESX1) (AA 28-55), (N-Term) antibodyESX1 适用: 人 WB 宿主: 兔 Polyclonal RB37249 unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- ESX Homeobox 1 (ESX1)
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别名
- ESX1
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背景
- Homeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.Synonyms: ESX1L, ESX1R, Homeobox protein ESX1
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基因ID
- 80712
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UniProt
- Q8N693
抗原
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