Emerin 抗体 (N-Term)
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Quick Overview for Emerin 抗体 (N-Term) (ABIN499790)
抗原
See all Emerin (EMD) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to Emerin.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Emerin antibody was raised against a 19 amino acid peptide from near the amino terminus of human Emerin.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Emerin (EMD)
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别名
- Emerin
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背景
- Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family that includes proteins such as LAP2 and MAN1. Each family member, including Emerin, has an ~40 amino acid LEM-domains that binds barrier-to-autointegration (BANF1), a conserved chromatin protein that also serves as a host cell component of retroviral integration complexes, including that of HIV. Emerin is anchored at the inner membrane of the nuclear envelope where it binds to nuclear intermediate filaments that are formed by lamin proteins. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.Synonyms: EDMD, EMD, STA
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基因ID
- 2010
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NCBI登录号
- NP_000108
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UniProt
- P50402
抗原
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