EFHD2 抗体 (N-Term)
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Quick Overview for EFHD2 抗体 (N-Term) (ABIN499784)
抗原
See all EFHD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- EFHD2 antibody was raised against a 16 amino acid peptide near the amino terminus of human EFHD2.
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亚型
- IgG
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anti-EF-Hand Domain Family, Member D2 (EFHD2) (C-Term) antibody
Verified EFHD2 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-EF-Hand Domain Family, Member D2 (EFHD2) (AA 2-240) antibodyEFHD2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EF-Hand Domain Family, Member D2 (EFHD2) (AA 1-78) antibodyEFHD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-EF-Hand Domain Family, Member D2 (EFHD2) (N-Term) antibodyEFHD2 适用: 人, 小鼠, 大鼠, 斑马鱼, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: EFHD2 antibody can be used for detection of EFHD2 by Western blot at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))
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别名
- EFHD2
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背景
- EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.Synonyms: EF-hand domain-containing protein D2, SWS1, Swiprosin 1, Swiprosin-1
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基因ID
- 79180
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NCBI登录号
- NP_077305
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UniProt
- Q96C19
抗原
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