DRAM 抗体 (C-Term)
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Quick Overview for DRAM 抗体 (C-Term) (ABIN499772)
抗原
See all DRAM (DRAM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to DRAM.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- DRAM antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human DRAM.
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亚型
- IgG
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anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (AA 50-100) antibody
DRAM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (AA 70-119) antibodyDRAM1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (N-Term) antibodyDRAM1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (C-Term) antibodyDRAM1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (N-Term) antibodyDRAM1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
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别名
- DRAM1
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背景
- Damage-regulated autophagy modulator (DRAM) is a p53 target gene encoding a lysosomal protein that induces autophagy, a process that degrades cytosolic proteins and organelles. It has been suggested that activation of DRAM by p53 is simultaneous to the activation by p53 of one or more proapoptotic genes such as PUMA, Bax, etc., and that the signaling pathways regulated by these genes promote a full cell death response. By itself, DRAM cannot induce apoptosis, but the fact that it is inactivated in certain cancers highlights the importance of DRAM and suggests that autophagy may play a more important role in cancer than initially suspected. At least two different isoforms of DRAM are known to exist.Synonyms: DNA damage regulated autophagy modulator protein 1, DRAM, DRAM-1, FLJ11259
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基因ID
- 55332
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UniProt
- Q8N682
抗原
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