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DRAK2 抗体 (C-Term)

The 兔 多克隆 anti-DRAK2 antibody (ABIN499770) specifically detects DRAK2 in WB, IF 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN499770
发货至: 中国
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Quick Overview for DRAK2 抗体 (C-Term) (ABIN499770)

抗原

See all DRAK2 (STK17B) 抗体
DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

适用

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宿主

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克隆类型

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多克隆

标记

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This DRAK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    DRAK2 antibody was raised against a peptide corresponding to amino acids 351 to 365 of human DRAK2. It has no cross responses to DAP or ZIP kinases.

    纯化方法

    Ion exchange chromatography

    免疫原

    Human DRAK2 (C-Terminus) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1/500 to 1/1000. An approximately 45 kDa band can be detected. Theapproximately 70 kDa band is probably non-related to DRAK2 although it is peptideblockable. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

    别名

    STK17B / DRAK2

    背景

    Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases) (1). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues (1).Synonyms: DAP kinase-related apoptosis-inducing protein kinase 2, Serine/threonine-protein kinase 17B

    基因ID

    9262

    UniProt

    O94768
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