电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

DNAL1 抗体 (C-Term)

This anti-DNAL1 antibody is a 兔 多克隆 antibody detecting DNAL1 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499752
发货至: 中国

Quick Overview for DNAL1 抗体 (C-Term) (ABIN499752)

抗原

See all DNAL1 抗体
DNAL1 (Dynein, Axonemal, Light Chain 1 (DNAL1))

适用

  • 21
  • 15
  • 14
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 19
  • 2

克隆类型

  • 19
  • 2
多克隆

标记

  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DNAL1 antibody is un-conjugated

应用范围

  • 14
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    C-Term

    特异性

    This antibody reacts top DNAL1.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    DNAL1 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human DNAL1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    DNAL1 (Dynein, Axonemal, Light Chain 1 (DNAL1))

    别名

    DNAL1

    背景

    DNAL1 was identified as a potential candidate gene for primary ciliary dyskinesia (PCD), a genetically heterologous disorder characterized by chronic infections of the upper and lower airways that often leads to permanent lung damage, randomization of left/right body symmetry, and reduced fertility. DNAL1 is reported to be expressed solely in tissues carrying motile cilia for flagella and interacts with DNAH5, a protein that when mutated has been shown to result in PCD. It has been suggested that DNAL1 serves a regulatory function for DNAH5 activity in outer dynein arms of sperm flagella, respiratory cilia, and ependymal cilia. DNAL1 has also been recently identified as an HIV dependency factor (HDF), suggesting that DNAL1 may be an important drug target in HIV treatment. At least two isoforms of DNAL1 are known to exist.Synonyms: C14orf168, Dynein light chain 1 axonemal

    基因ID

    83544

    NCBI登录号

    NP_113615

    UniProt

    Q4LDG9
You are here:
Chat with us!