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DISC1 抗体 (Center)

This anti-DISC1 antibody is a 兔 多克隆 antibody detecting DISC1 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499748
发货至: 中国

Quick Overview for DISC1 抗体 (Center) (ABIN499748)

抗原

See all DISC1 抗体
DISC1 (Disrupted in Schizophrenia 1 (DISC1))

适用

  • 71
  • 23
  • 16
  • 1
人, 小鼠

宿主

  • 74
  • 4
  • 1
  • 1

克隆类型

  • 75
  • 7
多克隆

标记

  • 46
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DISC1 antibody is un-conjugated

应用范围

  • 45
  • 26
  • 24
  • 14
  • 14
  • 14
  • 11
  • 9
  • 9
  • 8
  • 4
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    特异性

    This antibody reacts to DISC1.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    DISC1 antibody was raised against a 18 amino acid peptide from near the center of human DISC1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    DISC1 (Disrupted in Schizophrenia 1 (DISC1))

    别名

    DISC1

    背景

    Disrupted in schizophrenia 1 (DISC1) is a candidate gene for susceptibility to schizophrenia. It was discovered through chromosomal analysis of a large Scottish family whose members exhibited schizophrenia and related psychiatric disorders. Through yeast two-hybrid screening, it was discovered that DISC1 interacts with many members of the centrosome and cytoskeletal system including MAP1A and Nudel. More recently, DISC1 has been found to regulate the transport of a complex containing Nudel, the lissencephaly-1 (LIS1) protein, and 14-3-3e from neuronal cell bodies to the axons by the action of the microtubule-dependent directed motor protein kinesin-1, also known as KIF5A. Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration, resulting in aberrant morphological development, suggesting that DISC1 plays a role in dendritic development and synapse formation. DISC1 has at least four known isoforms.Synonyms: DISC-1, Disrupted in schizophrenia 1 protein, KIAA0457

    基因ID

    27185

    NCBI登录号

    NP_061132

    UniProt

    Q9NRI5

    途径

    Regulation of Cell Size
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